Inspired by those 1980s kids’ toy TV advertisements, ‘Nanomachines’ explains genetics and targeted genetic treatments for Huntington’s disease in a fun and accessible format for kids of all ages! We at UCL Huntington’s Disease Centre developed this film in collaboration with UCLH NIHR Biomedical Research Centre and Greg Foot.
In our annual roundup of what’s new and what’s hot in Huntington’s disease research for the Huntington’s Disease Society of America Annual Convention, Jeff Carroll and I talked about huntingtin lowering, the impact of covid-19 on HD research and much more. Featuring the world premiere of our ‘Nanomachines’ gene-silencing explainer!
In this feature-length PBS documentary by Oscar-winning director Ken Burns, I talked about our huntingtin-lowering clinical trial project .
Arabic language feature about the HTTRx trial program.
Huw Edwards discusses the IONIS-HTTRx trial success with Sarah Tabrizi and James Gallagher. Featuring footage of Ed Wild, Lauren Byrne and Filipe Brogueira Rodrigues.
Dr Ed Wild with Jenni Murray and HD family member Susan Fletcher, talk about Huntington’s disease on Woman’s Hour. Broadcast 15th July 2016.
Dr Ed Wild of UCL Huntington’s Disease Centre (Institute of Neurology) delivers an update on Ionis Pharmaceuticals 443139-CS1 trial, testing HTTRx, a huntingtin-lowering antisense oligonucleotide or ‘gene silencing’ drug in Huntington’s disease patients.
Dr Ed Wild and Dr Jeff Carroll present a live recording of their 2016 research update at the 2016 Huntington’s Disease Society of America Convention in Baltimore, entitled “The Best Time to Plant a Tree”, including updates on the Teva Pride-HD and Legato studies, Pfizer’s Amaryllis study, and Ionis Pharmaceuticals’ HTTRx ‘gene silencing’ trial.