In this Lancet Neurology paper, we report neurofilament light chain as the first blood biomarker to predict onset, progression and neurodegeneration in Huntington’s disease.
BBC News – Huntington’s disease trial test is ‘major advance’
Daily Telegraph – Simple blood test holds out hope for Huntington’s disease breakthrough
I’m a Consultant Neurologist at the National Hospital for Neurology and Neurosurgery in London’s Queen Square. I run clinics in general neurology, neurogenetic movement disorders and Huntington’s disease.
I’m an MRC Clinician Scientist at UCL Institute of Neurology, and a Principal Investigator at UCL Huntington’s Disease Centre. My clinical research aims to accelerate the development of new therapies to make a real difference for people impacted by Huntington’s disease.
I believe that scientists have a duty to make their work accessible and understandable to the people who need it most. In 2010, I co-founded HDBuzz, an online source of reliable, impartial, easy-to-understand information about HD research. HDBuzz is now the world’s foremost HD research news source. In recognition of this, I was awarded the 2012 Michael Wright Community Leadership Award by the Huntington Society of Canada and the 2014 Research Award by the Huntington’s Disease Society of America.
I have authored 7 book chapters and over 70 peer-reviewed publications. I serve on the medical advisory panel of the Huntington’s Disease Association, the Editorial Boards of Journal of Huntington’s Disease and PLoS Currents: Huntington’s Disease and the steering committee to the UK All-Party Parliamentary Group on Huntington’s disease. I am the Lead Facilitator of the European Huntington’s Disease Network‘s Biomarkers Working Group and an emeritus member of the Network’s Scientific and Bioethical Advisory Committee.
Queen Square Neurologist