Hannah Devlin speaks with Dr Ed Wild, from UCL, about Huntington’s and whether a new drug could slow its progression. And she hears from Roger, who was diagnosed with Huntington’s four years ago and his wife, Brenda.
Johnson et al 2018
Byrne et al 2017
Wild & Tabrizi 2017
Therapies targeting DNA and RNA in Huntington’s disease. Lancet Neurology 2017
Overview of huntingtin-lowering therapies in development.
Bates et al 2015
Huntington Disease. Nat Rev Disease Primers. 2015: 15005
Overview of HD biology, clinical features and therapeutic landscape
G Bates (textbook)
Huntington’s Disease (Oxford Monographs on Medical Genetics), 3rd ed. Ed G Bates, L Jones & S Tabrizi. Oxford University Press. ISBN 978-0199929146
Comprehensive monograph on HD
Wild & Tabrizi 2014
Targets for future clinical trials in Huntington’s disease: What’s in the pipeline? Mov Disord. 2014 Sep 15;29(11):1434-45. PMID: 25155142.
Arabic language feature about the HTTRx trial program.
Huw Edwards discusses the IONIS-HTTRx trial success with Sarah Tabrizi and James Gallagher. Featuring footage of Ed Wild, Lauren Byrne and Filipe Brogueira Rodrigues.